It ends where it begins
It ends with the Conquer.

Reunited with the gang, Ishika finds out there are more Malignants than she thought: a boy chained in iron, a forsaken soul and a girl who never stands down. Together they have to break the centuries old curse.

Northacus 1637: Panic has wrecked the alleyways of Northacus. An unknown force is at work. Amare should figure out her destiny as she tracks down Derues, trying to put a stop to it all.
Betrayal, war and madness is boiling...

If one of them can't stop this chaos, that's where the ends meet.